Glycan Modification and Its Effect on Monoclonal Antibody Therapeutics: Enhancing Effectiveness Through Glycan Engineering
Introduction Glycosylation is a principal biochemical system that contains the attachment of carbohydrates to proteins, forming glycoproteins. This amendment performs a vital role in many different organic services, including protein steadiness, folding, and cell interactions. In the context of monoclonal antibodies (mAbs), glycosylation critically influences their therapeutic efficacy. As researchers delve deeper into glycoengineering—an modern …